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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SPPL2C
All Species:
13.33
Human Site:
Y38
Identified Species:
36.67
UniProt:
Q8IUH8
Number Species:
8
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8IUH8
NP_787078.1
684
74503
Y38
S
E
N
W
S
K
D
Y
C
I
L
F
S
S
D
Chimpanzee
Pan troglodytes
XP_523673
684
74537
Y38
S
E
N
W
S
K
D
Y
C
I
L
L
S
S
D
Rhesus Macaque
Macaca mulatta
XP_001115879
684
74573
Y38
S
E
N
W
S
K
D
Y
C
I
L
F
S
S
D
Dog
Lupus familis
XP_548046
660
70155
N29
V
V
H
V
V
S
E
N
W
S
K
D
Y
C
V
Cat
Felis silvestris
Mouse
Mus musculus
A2A6C4
690
76248
Y44
S
K
N
W
S
K
D
Y
C
V
L
Y
S
S
D
Rat
Rattus norvegicus
Q5PQL3
577
63718
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001507224
648
71872
N31
G
I
P
V
P
S
K
N
Y
C
M
I
F
N
P
Chicken
Gallus gallus
Q5F383
596
66378
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_782326
512
56836
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.8
94.4
70.4
N.A.
69.1
41.5
N.A.
33
45.3
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
33.3
Protein Similarity:
100
99.1
96.1
78.3
N.A.
80.2
57.5
N.A.
51
60
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
47.5
P-Site Identity:
100
93.3
100
0
N.A.
80
0
N.A.
0
0
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
0
P-Site Similarity:
100
93.3
100
13.3
N.A.
100
0
N.A.
13.3
0
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
0
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
45
12
0
0
0
12
0
% C
% Asp:
0
0
0
0
0
0
45
0
0
0
0
12
0
0
45
% D
% Glu:
0
34
0
0
0
0
12
0
0
0
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
23
12
0
0
% F
% Gly:
12
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
12
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
12
0
0
0
0
0
0
0
34
0
12
0
0
0
% I
% Lys:
0
12
0
0
0
45
12
0
0
0
12
0
0
0
0
% K
% Leu:
0
0
0
0
0
0
0
0
0
0
45
12
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
12
0
0
0
0
% M
% Asn:
0
0
45
0
0
0
0
23
0
0
0
0
0
12
0
% N
% Pro:
0
0
12
0
12
0
0
0
0
0
0
0
0
0
12
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% R
% Ser:
45
0
0
0
45
23
0
0
0
12
0
0
45
45
0
% S
% Thr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% T
% Val:
12
12
0
23
12
0
0
0
0
12
0
0
0
0
12
% V
% Trp:
0
0
0
45
0
0
0
0
12
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
45
12
0
0
12
12
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _